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Scientists unleash power of genetic data to identify disease risk

Added: 16.01.2018 9:56 | 0 views | 0 comments


Massive banks of genetic information are being harnessed to shed new light on modifiable health risks that underlie common diseases. Researchers have pioneered a method to integrate data from multiple large-scale studies to assess risk factors such as body mass index (BMI) and cholesterol levels, and their association with diseases including type two diabetes and heart disease.


Camelina oil improves blood lipid profile

Added: 08.01.2018 10:13 | 3 views | 0 comments


The use of camelina oil reduces overall and LDL cholesterol levels in persons with impaired glucose metabolism, according to a new study.

Tags: Oil

Multi-gene test predicts early heart disease risk

Added: 08.01.2018 9:01 | 2 views | 0 comments


A risk score based on multiple genetic differences, or polygenic test, predicted significantly more cases of early heart disease than standard tests for single genetic defects. The polygenic test predicted a high risk for early-onset heart disease in 1 out of 53 individuals, compared to 1 in 256 for the most frequent single genetic defect.


Multiple sclerosis: Cholesterol crystals prevent regeneration in central nervous system

Added: 04.01.2018 15:34 | 3 views | 0 comments


Multiple Sclerosis is a chronic inflammatory disease of the central nervous system, in which the immune cells attack myelin sheaths. Regeneration of myelin sheaths is necessary for patients to recover from MS relapses. Nevertheless, the ability to regenerate decreases with age.

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Promising anti-obesity drug shrinks fat without suppressing appetite

Added: 04.01.2018 15:34 | 2 views | 0 comments

Given the ever-increasing obesity epidemic, researchers have discovered a promising developing drug that has been shown to selectively shrink excess fat by increasing fat cell metabolism. The drug significantly reduces body weight and blood cholesterol levels without lowering food intake in obese mice, according to a recent study.

Tags: Cher

New cholesterol calculation may avoid need to fast before testing, study suggests

Added: 02.01.2018 10:33 | 2 views | 0 comments

In a direct comparison study, researchers have added to evidence that a newer method of calculating so-called 'bad cholesterol' levels in the blood is more accurate than the older method in people who did not fast before blood was drawn.

Tags: Drake, Cher

Potential path to repair MS-damaged nerves

Added: 26.12.2017 10:49 | 2 views | 0 comments


Gene expression in specific cells and in specific regions can provide a more precise, neuroprotective approach than traditional treatments for neurological diseases. For multiple sclerosis, specifically, increasing cholesterol synthesis gene expression in astrocytes of the spinal cord can be a pathway to repair nerves that affect walking.

Tags: EU, Walking

Health benefits of swapping animal proteins for plant proteins

Added: 20.12.2017 9:17 | 2 views | 0 comments


Substituting one to two servings of animal proteins with plant proteins every day could lead to a small reduction in the three main cholesterol markers for cardiovascular disease prevention, a new study suggests.


A spring-loaded sensor for cholesterol in cells

Added: 07.12.2017 13:22 | 3 views | 0 comments

New research explains how an enzyme acts as a kind of thermostat that responds to and adjusts levels of cholesterol in the cell. This insight could lead to new strategies for combating high cholesterol.


Diet success may depend on your DNA

Added: 30.11.2017 17:02 | 2 views | 0 comments

We can add one more thing to the list of traits affected by genetics: how our bodies respond to a particular diet. Research in animal models with different genetics shows that one diet really doesn't fit all, and what works for some may not be best for others, according to a new study.

Tags: Animals, DNA

Bacterial fats, not dietary ones, may deserve the blame for heart disease

Added: 28.11.2017 9:25 | 4 views | 0 comments

Heart disease and fatty clogs in the arteries go hand in hand. But new evidence suggests the fatty molecules might come not only from what you eat, but from the bacteria in your mouth, scientists report. The research may explain why gum disease is associated with heart trouble.


Cardiorespiratory fitness is essential to reduce risk of coronary heart disease

Added: 17.11.2017 19:51 | 3 views | 0 comments

New findings emphasize the importance of measuring and maintaining aerobic fitness.

Tags: Rita Ora

Vegan diet as lifestyle choice and the need for risk communication

Added: 17.11.2017 19:27 | 5 views | 0 comments

Tofu sausages on the barbecue, followed by cake made with bananas instead of eggs? There is no doubt that the vegan diet is in vogue. Alongside the proven positive effects on health, however, there are also risks.

Tags: USA, No Doubt

Molecular guardian defends cells, organs against excess cholesterol

Added: 16.11.2017 13:27 | 3 views | 0 comments

Medical researchers have illuminated a critical player in cholesterol metabolism that acts as a molecular guardian in cells to help maintain cholesterol levels within a safe, narrow range. Known as Nrf1, it both senses and responds to excess cholesterol, and could represent a potential new therapeutic target in a multitude of diseases where cholesterol metabolism is disrupted.

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PCSK9 Inhibitor improves outcomes for patients with peripheral artery disease

Added: 14.11.2017 16:26 | 4 views | 0 comments

LDL-cholesterol-lowering drug evolocumab reduced risk of major cardiovascular events and major adverse limb events among peripheral artery disease sub-population from the FOURIER trial. A new sub-analysis of the FOURIER clinical trial, however, now offers information on the safety and effectiveness of giving the PCSK9 inhibitor evolocumab on top of statin therapy to patients with peripheral artery disease.

Tags: Rita Ora, PC

New strategies to increase 'good' cholesterol?

Added: 13.11.2017 19:50 | 13 views | 0 comments

After decades of individual attempts to identify the structure of the main building block of HDL (high-density lipoproteins), the so-called 'good' cholesterol that associates with protection from cardiovascular disease, a research team representing eight academic institutions across the US and Australia has come to agreement on a predictive model.

Tags: Australia

Heart attack and stroke patients prescribed statin medication upon discharge have better outcomes

Added: 13.11.2017 16:28 | 6 views | 0 comments

Patients with a prior history of heart attacks or stroke have better outcomes when cholesterol-lowering medications are used after they're discharged from the hospital, according to a new study.

Tags: Hospitals

Follow-up cholesterol testing reduces risk of reocurrence for heart attack, stroke patients

Added: 13.11.2017 9:55 | 5 views | 0 comments

If you have a heart attack or stroke, it's important to get your 'bad' cholesterol measured by your doctor on a follow up visit. Researchers have found that one step is significantly associated with a reduced risk of suffering another serious cardiovascular episode.

Tags: Rita Ora, Cher

10-year fall in blood cholesterol of Malaysia heart attack patients suggests statin impact

Added: 03.11.2017 8:58 | 8 views | 0 comments

A ten-year decline in the blood cholesterol of heart attack patients in Malaysia suggests that statins are having a positive impact, according to an observational study in nearly 49,000 patients.

Tags: Malaysia

Less than half of patients prescribed new cholesterol drug receive insurance approval

Added: 30.10.2017 8:47 | 5 views | 0 comments

In the largest study of its kind, less than half of patients prescribed the new class of cholesterol drugs, PCSK9 inhibitors, received insurance approval even if patients had atherosclerotic cardiovascular disease (plaque build-up of the arteries) or markedly elevated bad cholesterol. The most significant factor associated with approval was insurance type, with Medicare patients more likely to be approved than those with private insurance.

Tags: PC

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