A new study finds that carvedilol, a drug typically used to treat high blood pressure, can protect against the sun-induced cell damage that leads to skin cancer. The research could lead better ways to protect our skin from the sun.
Risks from firearms actually come from both ends of the barrel, according to a new study. Individuals at firing ranges are exposed to very high amounts of lead from shooting firearms, and exposure is as high at outdoor firing ranges as it is at indoor ranges.
The characteristics of human skin are heavily dependent on the hydration of the tissue -- in simple terms, the water content. This also changes its interaction with textiles. Up to now, it has only been possible to determine the interaction between human skin and textiles by means of clinical trials on human subjects. Now, researchers have developed an artificial gelatine-based skin model that simulates human skin almost perfectly.
Scientists have identified the gene responsible for generating acylceramide, the key lipid in forming the skin barrier that protects us from pathogens, allergens and other harmful substances. This finding could prove crucial in developing medicines for treating atopic dermatitis and ichthyosis.
Clinicians and dermatologists have seen a rise in demand for minimally invasive laser-based treatments, including tattoo removal. However, it is difficult for the laser light to be perfectly and selectively absorbed by only the targeted birthmark or tattoo. Now, researchers have developed instruments that transmit laser light into the tissue through direct contact. The techniques developed will reduce safety concerns in laser dermatology by improving laser transmission.
Researchers have developed a contactless and wireless camera system to continuously monitor the vital signs of premature babies. This system could replace skin sensors, which cause false alarms nearly 90 percent of the time.
Throughout the course of a leprosy infection, patients often have episodes of painful inflammation affecting their skin and nerves. Researchers have continuously struggled with finding effective drugs to treat these so-called 'type 1 reactions,' and now one more study has come up empty-handed. The immune-suppressant azathioprine did not improve the standard of care treatment with steroids, researchers report.
Alcohol intake was associated with higher rates of invasive melanoma among white men and women, according to a study. White wine carried the most significant association, and the increased risk was greater for parts of the body that receive less sun exposure, the study showed.
For the two-thirds of kidney stone patients who need more than just extra hydration to pass their stones, physicians are eager to find non-surgical ways to help. Now, a new review of the medical literature suggests alpha blockers may be useful in some cases.
A newly discovered bacterial protein produced in the zebrafish gut triggers insulin-producing beta cells of the pancreas to multiply during early larval development, say researchers. The research potentially has human health implications. The findings, which could someday lead to new diabetes treatments, highlight the important role of resident microbes in development of the pancreas,
'Alpha-synuclein,' a protein involved in a series of neurological disorders including Parkinson's disease, is capable of traveling from brain to stomach and does so following a specific pathway, researchers have discovered. This study, carried out in rats, sheds new light on pathological processes that could underlie disease progression in humans.
Scientists report that GARP, a TGF-beta cell surface receptor, could be a novel diagnostic marker for breast, colon, and lung cancer. An antibody-based therapy targeting GARP prevented metastasis to the lung in a mouse model of breast cancer. Targeting GARP with an antibody could represent a novel addition to established immunotherapies that 'wake up' the immune system so that it can fight cancer.
A naturally-occurring compound called squalamine has been found to block the molecular process underlying Parkinson's disease and suppress its toxic effects. Although the findings are only preliminary, researchers suggest that they could provide the basis for a drug treating at least some of the symptoms of Parkinson's disease.